27 Oct What percentage of cancer are with metastasis
What percentage of cancer are with metastasis? (1 pt)
Explain what it means for a cancer cell to “intravasate” and how that is involved in the process of metastasis. (2 pts)
What is mesenchyme? (1 pt)
What does the term “EMT” stands for, in the cancer biology field? (1 pt)
Which cell type, lymphoid or myeloid, are considered the origin of most metastatic cancers? (1 pt)
Explain the myeloid hypothesis of metastasis. (2 pts)
Explain the main differences between the M1 and M2 macrophage phenotypes. (4 pts)
In this week’s lecture, what does “TAM” stand for? (1 pt)
What is the single most common hallmark of all cancer cells including those with metastatic potential? (1 pt)
Explain what hypoxia means. (1 pt
The origin of metastasis as a __________ disease, is in line with Paget’s proposed Seed and Soil Hypothesis. (1 pt)
This is arguably the most well-studied angiogenesis factor: ___________________ (1 pt)
Explain what angiogenesis inhibitors are/what they do. (2 pts)
What was the first naturally-occurring angiogenesis inhibitor? (1 pt)
Give two advantages of using natural angiogenesis inhibitors for cancer treatment? (2 pts)
(22 points total)
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