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The most important advantage of the transmission electron microscope (TEM) over the light microscope (LM) is its higher resolution.

Cellular Form and Function

1. The most important advantage of the transmission electron microscope (TEM) over the light microscope (LM) is its higher resolution.

 

True   False

 

2. If a cell doubled in diameter, it would have twice as much cytoplasm to maintain. True   False

 

3. In the plasma membrane, glycolipids and glycoproteins face toward the cytoplasm, while peripheral

 

proteins always face toward the ECF. True   False

 

4. A cell’s second messengers serve to transport material through cellular membranes.

 

True   False

 

5. Microvilli and cilia differ in their function, but have the same internal structure. True   False

 

6. Ligand-gated ion channels are membrane proteins that open or close in response to the binding of a

 

chemical. True   False

 

7. The greater the concentration gradient, the faster the diffusion rate.

 

True   False

 

8. Na+-K+ ATPase is a countertransport antiport carrier, which always requires energy. True   False

 

9. The sodium-glucose transport protein (SGLT) is one example of an active transport process involving a

 

uniport carrier. True   False

 

10. One example of pinocytosis is the uptake of low-density lipoproteins (LDLs) by endothelial cells.

 

True   False

 

11. Both the nucleus and the mitochondrion are surrounded by a two layer membrane. True   False

 

12. In most cells, the nucleus is the largest organelle. True   False

 

13. Ribosomes are made of proteins and RNA.

 

True   False

 

14. The Golgi complex makes peroxisomes, but not lysosomes. True   False

 

15. A crystal of calcium phosphate in the cytoplasm of a cell should be classified as an inclusion. True   False

 

Multiple Choice Questions

 

16. Which of the following statements is not a tenet of modern cell theory?

 

A. An organism’s structure and all of its functions are ultimately due to the activities of its cells.

 

B. All cells come only from preexisting cells.

 

C. All cells occupy space.

 

D. All organisms are composed of cells and cell products.

 

E. The cell is the basic structural and functional unit of life.

 

17. Cells were first discovered when a scientist named   observed cell walls in cork under a microscope.

 

A. Robert Hooke

 

B. Theodor Schwann

 

C. Louis Pastuer

 

D. Galen

 

E. Galileo

 

18. Cells that are thick in the middle and tapered toward the end are called         cells.

 

A. squamous

 

B. stellate

 

C. columnar

 

D. spheroid

 

E. fusiform

 

19. Most human cells range from 10 to 15 micrometers in diameter. What limits how large a cell can get?

 

A. A cell’s lifespan

 

B. Nutrients available in the environment of a cell

 

C. The relationship between its volume and length

 

D. The relationship between its length and surface area

 

E. The relationship between its volume and surface area

 

20. The fluid outside of a cell is called      .

 

A. cytosol

 

B. intracellular fluid

 

C. extracellular fluid

 

D. cytoplasm

 

E. nucleoplasm

 

21. Which of the following is not one of the three basic components of a cell?

 

A. Cytoplasm

 

B. Nucleus

 

C. Plasma membrane

 

D. Interstitial fluid

 

22. The flat-shaped cells found covering the skin are       in shape.

 

A. cuboidal

 

B. columnar

 

C. cylindrical

 

D. squamous

 

E. spherical

 

23. Although the transmission electron microscope (TEM) can magnify much more than a light microscope, even at identical magnifications the TEM has the advantage of     .

 

A. being able to produce photographs of the specimen

 

B. being able to work in a vacuum

 

C. being able to show individual molecules

 

D. producing higher resolution

 

E. working better with thinner tissue specimens

 

24. The most abundant molecules in the plasma membrane are                .

 

A. glycolipids

 

B. phospholipids

 

C. prostaglandins

 

D. proteins

 

E. cholesterol molecules

 

25. Membrane proteins that bind to signals by which cells communicate are called           .

 

A. receptors

 

B. enzymes

 

C. carriers

 

D. cell-identity markers

 

E. cell-adhesion molecules

 

26. A receptor protein in the plasma membrane will not bind to just any chemical in the extracellular fluid, but only to certain ones. This property is called         .

 

A. selectivity

 

B. specificity

 

C. efficac

 

y

 

D. saturation

 

E. fidelity

 

27. In its second-messenger role, cAMP activates enzymes called             , whose job is to regulate other enzymes by adding phosphate groups to them.

 

A. transmembrane proteins

 

B. peripheral proteins

 

C. kinases

 

D. glycocalyx

 

E. blockers

 

28. Most transmembrane proteins have               regions facing the intra- and extracellular fluid, and

 

                regions embedded in the phospholipid bilayer.

 

A. hydrophilic; hydrophilic

 

B. hydrophilic; hydrophobic

 

C. hydrophobic; hydrophobic

 

D. hydrophobic; hydrophilic

 

E. lipophilic; lipophobic

 

29. Channel protein gates respond to all these stimuli except      .

 

A. chemical messengers

 

B. ligands

 

C. changes in electrical potential (voltage) across a cellular membrane

 

D. physical deformation of a cellular membrane

 

E. water in the extracellular fluid

 

30. In the glycocalyx,      act like identification tags that enable the body to distinguish its own cells from foreign and diseased cells.

 

A. glycoproteins

 

B. lipoproteins

 

C. cholesterol molecules

 

D. phospholipids

 

E. cell-adhesion molecules

 

31. The fuzzy coat of carbohydrates on the outer surface of the plasma membrane that functions in cell identification is called the            .

 

A. brush border

 

B. glycocalyx

 

C. cholesterol coat

 

D. phospholipid bilayer

 

E. cell-adhesion molecule

 

32.          provide motility to a sperm cell,                act as sensory “antennae” in many cells, and

 

                increase a cell’s surface area.

 

 

 

 

 

A. Cilia; microvilli; flagella

 

B. Microvilli; cilia; flagella

 

C. Microvilli; flagella; cilia

 

D. Flagella; microvilli; cilia

 

E. Flagella; cilia; microvilli

 

33. The plasma membrane of cells lining the small intestine has , which are specialized for absorption of nutrients.

 

A. flagella

 

B. cilia

 

C. microvilli

 

D. a glycocalyx

 

E. dynein arms

 

34. Proteins that do not protrude into the phospholipid bilayer, but adhere to the surface of the plasma membrane, are called   

 

A. peripheral proteins

 

B. channel proteins

 

C. glycoproteins

 

D. integral proteins

 

E. transmembrane proteins

 

35. A protein that is bound to a carbohydrate is called a .

 

A. phosphoprotein

 

B. proteocalyx

 

C. glycoprotein

 

D. lipoprotein

 

E. phospholipid

 

36. The plasma membrane is mostly made of molecules that have hydrophilic heads and hydrophobic tails. These molecules are called       .

 

A. proteoglycans

 

B. glycolipids

 

C. glycoproteins

 

D. phospholipids

 

E. lipoproteins

 

37. ATP is consumed when          transfer solutes from one side of the membrane to the other.

 

A. receptors

 

B. pumps

 

C. cell-adhesion molecules

 

D. channels

 

E. cell-identity markers

 

38. Two solutions are separated by a selectively permeable membrane. If solution A has a higher concentration of a nonpermeating solute than solution B, then       .

 

A. the solute will pass down its concentration gradient from solution A to B

 

B. the solute will pass down its concentration gradient from solution B to A

 

C. water will pass down its concentration gradient from solution A to B

 

D. water will pass down its concentration gradient from solution B to A

 

E. neither the solute nor water will diffuse

 

39.          is the process in which   forces water and small solutes, such as salts, through narrow clefts between capillary cells.

 

A. Filtration; hydrostatic pressure

 

B. Osmosis; hydrostatic pressure

 

C. Active transport; osmotic pressure

 

D. Active transport; hydrostatic pressure

 

E. Osmosis; osmotic pressure

 

40. Water flows through a selectively permeable membrane in a process called , but water molecules cross the membrane more easily through channels of transmembrane proteins called

 

 A. osmosis; water pumps

 

B. osmosis; aquaporins

 

C. osmosis; uniport

 

D. filtration; aquaporins

 

E. filtration; water pumps

 

41. Insulin is taken up, via endocytosis, by the endothelial cells that line blood capillaries. Then, it’s transported across the cell to the other side, where it is released. This transport is called             .

 

A. pinocytosis

 

B. receptor-mediated phagocytosis

 

C. passive transport

 

D. facilitated transport

 

E. transcytosis

 

42. Sodium and glucose are transported together from the intestinal lumen into an intestinal cell. The carrier protein is a(n)                and the process is called               .

 

A. symport; cotransport

 

B. symport; countertransport

 

C. antiport; countertransport

 

D. antiport; cotransport

 

E. uniport; facilitated diffusion

 

43. The sodium-potassium (Na+-K+) pump transports both sodium and potassium           their concentration gradients in a process called    .

 

A. up; active transport

 

B. up; facilitated transport

 

C. up; cotransport

 

D. down; active transport

 

E. down; countertransport

 

44. A red blood cell is placed in a hypertonic solution. This means the concentration of solutes in the solution is  than the concentration of solutes in the intracellular fluid, and will cause the cell to

 

A. higher; swell

 

B. lower; swell

 

C. higher; shrink

 

D. lower; shrink

 

E. lower; burst

 

45. What do facilitated diffusion and active transport have in common?

 

A. Both involve transport of a solute up its concentration gradient.

 

B. Both involve transport of a solute down its concentration gradient.

 

C. Both involve the use of energy provided by ATP.

 

D. Neither require ATP to function.

 

E. Both are examples of carrier-mediated transport.

 

46. The number of particles of a solute in a solution is described by its    . The ability of a solution  to affect the fluid volume in a cell is referred to as its           .

 

A. tonicity; osmolarity

 

B. osmolarity; diffusion

 

C. osmolarity; tonicity

 

D. osmolarity; molarity

 

E. tonicity; diffusion

 

47. Which of the following processes could occur only through a cellular membrane?

 

 

 

 

 

A. Facilitated diffusion

 

B. Simple diffusion

 

C. Filtration

 

D. Osmosis

 

E. Active transport

 

48. Which of the following is not a method by which particles can leave a cell?

 

A. Active transport

 

B. Exocytosis

 

C. Simple diffusion

 

D. An antiport system

 

E. Pinocytosis

 

49. White blood cells engulf bacteria by means of             .

 

A. phagocytosis

 

B. cotransport

 

C. pinocytosis

 

D. active transport

 

E. receptor-mediated endocytosis

 

50. Which of the following is not a function of the Na+-K+ pump?

 

A. Heat production

 

B. Transport of Na+ into the cell and K+ out of the cell

 

C. Secondary active transport

 

D. Regulation of cell volume

 

E. Maintenance of membrane potential

 

51. The term      refers to a membrane that allows some things to pass through it, but not others.

 

A. selectively permeable

 

B. glycocalyx

 

C. phospholipid bilayer

 

D. specificity

 

E. carrier-mediated

 

52. Cellular membranes are permeable to            , but impermeable to     .

 

 

 

 

 

A. nutrients; wastes

 

B. proteins; nutrients

 

C. phosphates; wastes

 

D. nutrients; proteins

 

E. wastes; nutrients

 

53. A patient was severely dehydrated, losing a large amount of fluid. The patient was given intravenous fluids of normal saline. Normal saline is  to your blood cells and is about NaCl.

 

A. isotonic; 9%

 

B. isotonic; 0.9%

 

C. hypertonic; 9%

 

D. hypotonic; 0.9%

 

E. hypotonic; 9%

 

54. Which of these is an example of active transport?

 

A. Diffusion of oxygen from a place of high concentration to a place of lower concentration

 

B. Facilitated diffusion of K+

 

C. Transport of glucose down its concentration gradient

 

D. Transport of Na+ from a place of low concentration to a place of higher concentration

 

E. Transport of Cl- following its concentration gradient

 

55. Which of these brings nonspecific material into a cell?

 

A. Phagocytosis

 

B. Receptor-mediated endocytosis

 

C. Transcytosis

 

D. Pinocytosis

 

E. Exocytosis

 

56. Which of the following is not a membranous organelle?

 

A. Mitochondria

 

B. Ribosome

 

C. Nucleus

 

D. Endoplasmic reticulum

 

E. Golgi complex

 

57. Among other functions, hepatocytes (liver cells) are specialized for detoxifying drugs or other chemicals. Hepatocytes have large amounts of   .

 

A. DNA

 

B. smooth endoplasmic reticulum

 

C. microtubules

 

D. cilia

 

E. centrioles

 

58. What function would immediately cease if the ribosomes of a cell were destroyed?

 

A. Exocytosis

 

B. Active transport

 

C. Ciliary action

 

D. Protein synthesis

 

E. Osmosis

 

59. What organelle is most active in causing programmed cell death?

 

A. Rough endoplasmic reticulum

 

B. Nucleus

 

C. Centriole

 

D. Lysosome

 

E. Mitochondrion

 

60. Muscle cells contain numerous           to serve their high demand for ATP.

 

A. ribosomes

 

B. lysosomes

 

C. mitochondria

 

D. inclusions

 

E. Golgi vesicles

 

61. Which organelle synthesizes steroids in the ovary and stores calcium in muscle cells?

 

A. Smooth endoplasmic reticulum

 

B. Rough endoplasmic reticulum

 

C. Nucleus

 

D. Mitchondrion

 

E. Golgi complex

 

62.          play an important role in cell division, and they are made of         .

 

A. Mitochondria; microtubules

 

B. Ribosomes; intermediate filaments

 

C. Nucleoli; microfilaments

 

D. Centrioles; microtubules

 

E. Inclusions; centrosomes

 

63.          synthesize(s) carbohydrates and put(s) finishing touches on proteins synthesized at

 

A. Smooth ER; rough ER

 

B. The Golgi complex; rough ER

 

C. Smooth ER; the Golgi complex

 

D. The Golgi complex; smooth ER

 

E. Ribosomes; smooth ER

 

64.          decompose fatty acids, and detoxify alcohol, free radicals, and drugs.

 

A. Lysosomes

 

B. Microvilli

 

C. Inclusions

 

D. Peroxisomes

 

E. Golgi vesicles

 

65. Which of the following organelles is not involved in protein synthesis?

 

A. Smooth ER

 

B. Rough ER

 

C. The Golgi complex

 

D. The nucleus

 

E. Ribosomes

 

66. Which of the following gives a cell structural support, determines the shape of a cell, and directs the movement of substances through a cell?

 

A. Cholesterol

 

B. The nucleus

 

C. The plasma membrane

 

D. The Golgi complex

 

E. The cytoskeleton

 

67. Which of the following is not associated with the composition of the cytoskeleton?

 

A. Microfilaments

 

B. Microtubules

 

C. Cilia

 

D. Intermediate filaments

 

E. Terminal web

 

68. Which of the following organelles sorts, cuts, splices, and packages newly formed proteins intomembrane- bound vesicles?

 

A. Smooth ER

 

B. Rough ER

 

C. Golgi complex

 

D. Mitochondrion

 

E. Nucleolus

 

69. Which of the following is a double-membraned organelle consisting of a matrix and cristae?

 

A. Mitochondrion

 

B. Rough ER

 

C. Smooth ER

 

D. Golgi complex

 

E. Nucleolus

 

70. Which of the following is not considered an inclusion?

 

A. Lysosome

 

B. Fat droplet

 

C. Glycogen granule

 

D. Bacterium

 

E. Dust particle

 

71. Accumulated cell products that are never enclosed in a unit membrane are called     .

 

A. organelles

 

B. inclusions

 

C. microtubules

 

D. microfilaments

 

E. centrioles

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